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Molecular Epidemiology and Ecology of Yersinia Species in the Transboundary Plague Endemic Territory in Georgia and Azerbaijan

Project

Molecular Epidemiology and Ecology of Yersinia Species in the Transboundary Plague Endemic Territory in Georgia and Azerbaijan

The objective of this project is to unravel the complexities of the co-existing diversity of Yersinia strains, specifically emphasizing characterization of strains belonging to Y. pseudotuberculosis species complex. Particular attention is given to the analysis of atypical Y. pestis strains (unusual morphological and biochemical characteristics, phage-sensitivity, plasmid composition, etc.), since standard surveillance may fail to detect these strains. The aims to achieve this objective include:

  • Ecological surveys targeting rodent populations in the transboundary focus located in both Georgia and Azerbaijan;
  • Development of culturing and polymerase chain reaction (PCR)-based procedures for detection of multiple strains of Yersinia;
  • Molecular screening of the collected rodent and flea samples;
  • Comparative analysis of the genomes of strains of Yersinia species both obtained during the field work of the proposed study and archived in the collections of isolates of the organizations of foreign collaborators; and 
  • Spatial analysis of distribution of strains of Yersinia species.

Risk Area(s) covered

Biological

Activities

Knowledge Sharing/Best Practices

Beneficiary Countries

Azerbaijan
Georgia

Beneficiary Regions

Central Asia

Budget

1541000 USD

Status

Active
Start Date: September 1, 2017
End Date: May 31, 2021

ASI Database Release

Providers and Implementers ?

Related Projects & Programs

Contacts

Name Position Agency/Department/Org Note
Mr Todd Perry Special Coordinator, UNSCR 1540
Department of State
United States
Mr Stephen Knight Point of Contact
United States Mission to the United Nations
United States

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